The enzyme that eats scar tissue

Anyone who’s undergone ORIF surgery, as I have, knows the resulting scar tissue causes pain and is a huge obstacle in regaining full range of motion. Conventional means of breaking up scar tissue actually result in the formation of new scar tissue. 

But there’s an effective solution that’s not well known outside of Europe and that is the enzyme serrapeptase. And after testing it myself for 90 days, I’m ready to spread the word.

comparing left and right ankles after orif surgery
The left ankle is slightly larger after ORIF surgery

What is serrapeptase

Serrapeptase (also known as serratiopeptidase) is an enzyme that comes from bacteria produced by the silkworm. It’s what helps the silkworm dissolve its cocoon. As a proteolytic enzyme, it breaks down protein into smaller pieces that can be digested and removed from the body.

Uses for serrapeptase

Serrapeptase reduces inflammation, swelling and pain after surgery. 

It can eat dead tissue, blood clots, cysts and arterial plaque. 

It breaks up biofilm produced by harmful bacteria and fungus, thereby making antibiotics more effective. 

It thins mucus, promotes normal mucus levels and is used to treat chronic respiratory diseases.

Use with caution

First of all, you need to choose a supplement that is enteric coated to survive stomach acid. The one I got is from iSerra which is maximum strength and time released.

iserra serrapeptase

Also, serrapeptase must be taken on an empty stomach with a full glass of water, at least an hour before eating first thing in the morning or two hours between meals.

Because of its blood thinning properties, it should not be taken with blood thinners, aspirin, NSAIDs, garlic, turmeric and fish oil. If you have any concerns, check with your doctor first.

My experience taking serrapeptase

During the last four years since ORIF surgery, I’ve worked really hard to recover full range of motion. I came to realize that scar tissue was impeding my progress despite my efforts to break it up mechanically. 

The problems I had were ankle impingement and the feeling of tight bands pulling internally while flexing my foot. It also caused twinges and occasional pain in certain positions.

So I got 90 capsules and chose to take only one a day first thing in the morning. (It can be taken up to three times a day.) I cut down on fish oil and stopped taking turmeric. I don’t take any type of medication.

After three days I noticed the blood thinning properties when a small wound produced more bleeding than normal.

After one month I woke up one day with nausea and nearly threw up three times. I believe this was a Herxheimer reaction from fungus die-off. (I took a little charcoal for the next three days and had no more symptoms.)

Near the end of the 90 days, the ankle impingement was gone. The sensation of tight bands while flexing also went away.

comparing left and right ankles after orif surgery
Four years after ORIF surgery on left ankle

It’s been nearly three weeks since the pills ran out and my dorsiflexion has definitely improved. In a separate article I will be describing the exercises that are helping me get to the finish line.

I do still feel one tight point at the inner side of the ankle joint during dorsiflexion. If it doesn’t improve in the next month or so, I may go back on serrapeptase for another 90 days. However, I don’t intend to take it continually.

Additional reading

Although serrapeptase has been widely used in Europe and Asia for decades, there have not been a lot of clinical studies done. But here are some articles that may be of interest.

10 replies
  1. Lisa
    Lisa says:

    Hi Lynda,
    Thanks for this.
    Do you still have the hardware? If not, why did you have it removed. If so, has it caused any issues for you?

  2. Chad
    Chad says:

    Hi there. I had a 4 level back fusion 2 years ago and im having those tight bands as well. Surgeon said 100% there will be issues down the road with scar tissue so im planning to take daily for as long as it takes to dissolve it. Im taking 250k 1 x a day and today is day 3 so we shall see! I am also looking forward to feeling better and begin to absorb all the nutrients from food as im sure my gut lining has a coat of biofilm blocking that ability. We all have the biofilm issue but some are worse/better than others. Serrapeptase clears that out. Thank you for this post!

  3. Stephanie
    Stephanie says:

    Hi, I had a trimalleolar fracture in July 2020. I have 2 plates, 12 screws, and pins on my ligament. I describe the feeling as tight bands also. My PT thinks my hardware is preventing full range of motion, but my surgeon doesn’t think it’s that. I would love to try something that could help loosen some of the tight pulling that prevents me from being able to walk without a limp, and someday, maybe wear 2-3″ heels again! Thank you for the article!

  4. Lynn
    Lynn says:

    Thank you so much for taking the time to share your journey and all this information. It is tremendously helpful — and hopeful too.

    • [email protected]
      [email protected] says:

      Thank you, Lynn! I’m happy there’s some good coming from my experience. My message is definitely one of hope and empowerment. Have a great day!

  5. shawn harhouf
    shawn harhouf says:

    I broke my ankle in two places and ruined my ligament(doc made a new one during surgery) 5 weeks ago so I am still in a cast. Enjoyed your posts


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